100% pure HMB. Beta-hydroxy beta-methylbutyrate (HMB) is a metabolite of the amino acid Leucine. This means that it is a natural bi-product of the breakdown of leucine, a constituent of normal dietary protein.
Research suggests that regular HMB supplementation results in significant strength gains, prevents muscle breakdown, boosts the immune system and even lowers harmful cholesterol.
Please Note: Not all supplements are this pure. TORQ's RAW range provides a guarantee of purity and high potency. We use the highest quality pharmaceutical-grade, non-animal based material. We do not mix, blend or dilute.
HMB (Beta-hydroxy beta-methylbutyrate) is a metabolite of the amino acid Leucine. This means that it is a natural bi-product of the breakdown of leucine, a constituent of normal dietary protein. Small amounts of HMB are found in certain foods like catfish, alfalfa and it is a natural component of mother's milk, but generally speaking it's pretty scarce in the average diet. HMB was first discovered in the 1950's and has been studied for several decades, but only really became popular as a sporting supplement in the mid 90's.
HMB has been found to slow down the degradation of muscle protein as well as enhance muscle gain, which means that it possesses both anti-catabolic and anabolic qualities. Early research has demonstrated that HMB supplementation lowers cholesterol and helps strengthen the immune system too.
HMB supplements were first used in the farming industry to help farmers raise leaner cattle and keep them free from infection. Scientists who studied animals taking HMB found that it increased muscle growth, immune function and reduced subcutaneous fat (the fat stored directly under the skin).
More recent research with human subjects has shown similar benefits. A highly respected research scientist called Dr Steven Nissen and his research team at Iowa State University conducted a study to determine if HMB would prevent muscle breakdown in humans undergoing resistance training and whether differing levels of protein intake would affect muscle mass or strength. They also assessed the effects of training and HMB administration on body fat and lean body mass levels*.
The researchers found that HMB supplementation decreased muscle breakdown in the group that took 3grams. Muscle strength also increased by 18.4% in the 3gram group, compared with 8% in the placebo group and muscle mass also increased by 2.66lbs and 0.88lbs respectively.
HMB is derived from the essential amino acid leucine. Essential amino acids have to be delivered to the body via the diet and usually human HMB production averages around 0.2 to 0.4grams per day, depending on how much leucine is present in the diet. Researchers have experimented with high dietary doses of leucine to see if this results in higher HMB production and although this has worked, for HMB production to reach 'gram' quantities, you would need 20 to 50grams of leucine per day. Supplementing with these quantities of leucine can be incredibly expensive and is likely to upset your stomach. Therefore, supplementing directly with HMB makes for better cashflow and less intestinal discomfort.
In order to establish how HMB might work, researchers have formulated hypothyses and tested them. It is known that HMB improves the protein balance by reducing catabolism (breakdown) and increasing anabolism (build-up) of muscle, but it is not fully understood how this occurs. It was first thought that HMB might be blocking the enzymes that carry out this catabolic process or that HMB itself may be an integral part of the cell membranes. While neither of these hypotheses has been ruled out, scientists now believe that HMB is most likely to be a precursor to a vital component of cell membranes, cholesterol. Rest assured, HMB has also been found to reduce harmful LDL (low density lipoprotein) blood cholesterol levels too, so HMB supplementation could reduce the risk of heart disease as well.
**Ed Burke was consultant to Chris Carmichael, coach to Lance Armstrong (seven times Tour De France winner).
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